In 2013 Regina Actress had two Tamil releases, Kedi Billa Killadi Ranga by Pandiraj, in which Regina Actress was one of the two lead actresses, and Nirnayam. Kotha Janta directed by Maruthi was her first 2014 release. Regina Actress received positive response for her performance in the film. Deccan Chronicle wrote, “The star of the film is undoubtedly Regina Cassandra. Regina Actress looks cute and bubbly and delivers a delightful performance. She has done her character with ease and with the right expressions”.

Regina Actress is working opposite Nara Rohith under the direction of Tatineni Satya in Sankara,and she has also bagged the female lead role opposite Sai Dharam Tej in his upcoming film to be directed AS Ravi Kumar Chowdary. Apart from these two films, Regina Actress is also working on Ra Ra Krishnayya and Power in which she is playing a Bengali girl

Regina Actress was next seen in the Kannada film Suryakaanti by director K. M. Chaitanya of Aa Dinagalu fame. The film featured her alongside actor Chetan, and as she could not speak Kannada, she was told to act out scenes in English and add Kannada to it. The film won good reviews and performed moderately at the box office. It was announced that Regina Actress would feature in the Tamil film Maalai Pozhudhin Mayakathilaey alongside Adith Arun, but the film was eventually delayed and then restarted with a fresh cast. In 2012, she appeared in Shiva Manasulo Shruti by Tatineni Sathya, which was a remake of the 2009 Tamil film Siva Manasula Sakthi. She was next seen in the Telugu romantic-comedy, Routine Love Story, alongside Sundeep Kishan, which Regina Actresssigned even before her first release in Telugu. Both films were well received by the audience.